Anadrol Side Effects

Anadrol is an incredibly powerful oral steroid developed in the 1960s to treat a variety of medical conditions. Anadrol was shown to increase red blood cell counts and improve muscle synthesis in many patients with muscle wasting disorders. 

Because of its innate properties, bodybuilders interested in strength and muscle gains often turn to this compound.

However, there are some Anadrol side effects worth mentioning, and you should consider them before you start your cycle.

Anadrol Doses

While Anadrol is a powerful steroid that can produce results without a stack, most people who use it with a great deal of success choose to pair it with one of several injectable forms of testosterone.

It can also be paired with other oral steroids, but users should do this carefully since stacking oral steroids can greatly increase the risk of liver damage. Before creating a stack, users should carefully consider not only their personal preferences and tolerance, but also their overall goals.

The chart below will help you determine the proper dose, including the recommended anadrol cycle length based on dose size.

Dose TypeDose AmountCycle Length
Base (Moderate) Dose
50mg per day
Six weeks
Low Dose
25mg per day
Eight weeks
High Dose
100mg per day
Four weeks

As you can see, the higher your dose, the shorter your cycle should be. This is one of the absolute best ways to reduce the likelihood and severity of Anadrol side effects.


Of all the Anadrol side effects, liver toxicity (hepatotoxicity) is of the greatest concern. Most oral steroids are alkylated, which means they’ve been specially designed in such a way that they will still be useful to your body once they’ve been processed by your liver.

To reduce risk, it’s vital to use supplements like milk thistle, which serve as protections against potential damage; and drink plenty of water. It’s also important to use the lowest possible dose that provides you with benefits, and to adjust your cycle length based on your dose.

Other Anadrol Side Effects

  • This steroid may increase your blood pressure significantly, so anyone who has been diagnosed with high blood pressure should avoid it. It may also worsen blood lipid profile, so it’s important to see your doctor regularly for lab tests.
  • Some users report an increase in acne while using Anadrol. This is due to hormone fluctuations. Many users report that simple drug-store treatments, including astringents and medicated facial pads, help to keep oil and acne manageable.
  • Anadrol does have some estrogenic effects, and these may lead to Gynecomastia and other symptoms. It’s important to have a suitable aromatase inhibitor on hand to mitigate these risks.
  • If Anadrol is taken by women, it’s important to keep in mind that while effective even at lower doses, this steroid will cause virilization when taken for extended periods. Women should watch closely for signs of virilization for this reason and consider milder options as an alternative.
  • While lower doses have been known to increase Appetite, the reverse is true for larger doses.
  • One of the most hotly debated Anadrol side effects is its ability to cause male pattern baldness. No link between steroids and baldness exists, though there is research to suggest that Anadrol (and other steroids) can escalate baldness in men who are genetically predisposed.
  • Some users report gastrointestinal issues ranging from mild to severe; these often get better over time, and mild symptoms can be remedied with over-the-counter medications.
  • As with most steroids, Anadrol 50 will shut down natural testosterone production, so it’s important to plan and follow through with extensive post-cycle therapy.
  • Some users experience trouble sleeping for the first few days of their cycles, but this often resolves itself on its own as the body acclimates.

Mitigating the Side Effects

Anadrol is a powerful steroid, and its side effects can be quite severe if users don’t take the proper precautions. There are several tips for mitigating Anadrol side effects from the very start.

  • Gauge your personal tolerance. Like any other supplement or drug, not everyone responds to Anadrol in the same way. Some athletes, for example, may only need a 25mg daily dose to experience their desired Anadrol results, but others may find they need to take 75mg to 100mg per day. Along those same lines, someone may have moderate side effects at a 50mg dose while his or her friend experiences only mild Anadrol side effects at a 100mg dose. For this reason, beginners should start with a very low dose of 25mg per day and work their way up gradually to gauge their personal tolerance and response.
  • Anticipate the symptoms. Some of the milder side effects associated with Anadrol, such as diarrhea, nausea, and even difficulty in sleeping, will pass in time. In this case, it’s helpful to familiarize yourself with these symptoms, anticipate them, and handle them as they occur. For example, you can take medications to help ease diarrhea and nausea, and over-the-counter medications containing diphenhydramine can help ease you into Sleep at night without fear of dependence.
  • Use the right supplements. Two of the most frightening Anadrol side effects – gynecomastia and liver damage – are easily controlled by taking the right supplements alongside your cycle. For example, an aromatase inhibitor like Arimidex will block Estrogen conversion, which makes gynecomastia virtually impossible. While there’s no way to protect your liver 100%, the best ways to reduce your odds of liver damage include taking a Liver Care supplement, which is available online, drinking plenty of water, and using a milk thistle supplement that is sold in most pharmacies and drug stores.

Anadrol Side Effects

Who Should Avoid Taking Anadrol?

While it’s possible for otherwise healthy people to mitigate the risks associated with Anadrol side effects, there are some individuals for whom using Anadrol may be too risky to their health. You should not use Anadrol if you have (or have had) any of the following health conditions:

  • High cholesterol – Research has shown that Anadrol can worsen lipid profiles, and this can be dangerous for anyone who’s being treated for high cholesterol.
  • High blood pressure – Most anabolic steroids, including Anadrol, will raise blood pressure significantly. Individuals who have healthy blood pressures can tolerate this increase, but those who have high blood pressure or who are taking medications to reduce their blood pressure should avoid it.
  • Liver or kidney problems – Anadrol has been shown to cause liver and kidney damage when utilized over long periods of time. Otherwise healthy people can protect themselves by following Anadrol dosage and cycle length guidelines and by using products to help keep liver enzymes within normal ranges. However, individuals who have had liver or kidney problems should not use Anadrol.
  • Women who are pregnant or breastfeeding – It’s important that women who are nursing or pregnant avoid using anabolic steroids, including Anadrol, as these can cross the placenta and pass into breastmilk. As mentioned, it’s not the best option for women in the first place. Slightly safer alternatives include anavar or winstrol.
  • Enlarged prostate – Men who have been diagnosed with enlargement of the prostate gland should avoid using Anadrol as it can exacerbate the condition.
  • Heart conditions – Finally, anyone with a heart condition should avoid Anadrol, as well. It’s been shown to cause fluid retention, which can lead to edema and, in the worst-case scenario, congestive heart failure.

As with any compound, not everyone will experience the same side effects, and those who do may experience them in varying severity. Understanding Anadrol side effects will help you make better, more informed choices about how to reach your unique goals.